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Mycoplasma genitalium (Mgen)

Mycoplasma genitalium (Mgen)

Find the hidden STI that might be harming your patients

Detect Mgen with the FDA-cleared Aptima® Assay

Mycoplasma genitalium, or Mgen, is a bacterium that can cause cervicitis, pelvic inflammatory disease (PID), and male urethritis. It can coexist with other STIs and cause similar symptoms.

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Advanced testing amplifies awareness

Recently developed detection capabilities have increased awareness of Mgen as a common STI, prevalent in 10.2% of females and 10.6% of males.1,*
Patients with Mgen can be asymptomatic or can exhibit symptoms that are similar to (or coexist with) other common STIs, including chlamydia, gonorrhea, and/or trichomoniasis.

*Study population included symptomatic and asymptomatic subjects for both sexes.

Mgen can be harmful if left untreated

Detected in up to

30%
of women with clinical cervicitis2
  • Identified in up to 22% of PID cases2
  • Infected patients are 2 times more likely to acquire HIV3
  • Identified in up to 22% of PID cases2
  • Infected patients are 2 times more likely to acquire HIV3

Responsible for

30%
of persistent or recurrent urethritis in men4

Additionally, Mgen coinfection is common in men

  • C trachomatis: 35%5
  • N gonorrhoeae: 14%5
  • C trachomatis and N gonorrheae: 19%5

Additionally, Mgen coinfection is common in men

  • C trachomatis: 35%5
  • N gonorrhoeae: 14%5
  • C trachomatis and N gonorrheae: 19%5

With 1 test, diagnose the cause of your patient's symptoms and reduce risks of untreated infection.

Symptoms

  • Frequent urination
  • Abnormal vaginal or penile discharge
  • Vaginal irritation or itching
  • Pain during intercourse
  • Burning during urination
  • Abnormal vaginal bleeding between periods or after intercourse

Suspected pathogens

  • Chlamydia
  • Gonorrhea
  • Trichomoniasis
  • Mgen

One specimen

STI panels test for all 4 pathogens with 1 urogenital samplea

aSTI panels can be performed with any of the collection devices shown above.

Mgen can be highly resistant to first-line antibiotics; alternate treatment may be necessary to avoid serious complications.

Although STIs present with similar symptoms, each responds better to different medications. Mgen can be highly resistant to standard first-line antibiotics, in which case, other medications may be necessary to avoid serious complications.

Get the answers you and your patients need with 1 test from Quest

FDA-cleared Aptima Assay from Quest uses nucleic acid amplification testing (NAAT), the preferred method of detection per the CDC.6

Test name

Test code

TEST NAME

SureSwab®, Mycoplasma genitalium only, Real-Time PCR

TEST CODE

91475

TEST NAME

Sexually Transmitted Infections (STIs) Cervicitis Panel

Included tests:

Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital

SureSwab, Trichomonas vaginalis RNA, Qualitative, TMA

Mycoplasma genitalium, rRNA, TMA

TEST CODE

36962

TEST NAME

Sexually Transmitted Infections (STIs) Pelvic Inflammatory Disease (PID) Panel

Included tests:

Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital

SureSwab, Trichomonas vaginalis RNA, Qualitative, TMA

Mycoplasma genitalium, rRNA, TMA

TEST CODE

36965

TEST NAME

Sexually Transmitted Infections (STIs) Male Urethritis Panel

Included tests:

Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital

Trichomonas vaginalis RNA, Qualitative, TMA, Males

Mycoplasma genitalium, rRNA, TMA

TEST CODE

36964

TEST NAME

Sexually Transmitted Infections (STIs) Male Urethritis Panel Expanded

Included tests:

Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital

Trichomonas vaginalis RNA, Qualitative, TMA, Males

Mycoplasma genitalium, rRNA, TMA

SureSwab, Ureaplasma species, Real-Time PCR

TEST CODE

38288

All components of panels can be ordered separately: Chlamydia trachomatis RNA, TMA, Urogenital (test code 11361); Neisseria gonorrhoeae (test code 11362); Chlamydia/Neisseria gonorrhoeae RNA, TMA, Urogenital (test code 11363); SureSwab Trichomoniasis RNA, Qualitative, TMA (test code 19550); SureSwab Ureaplasma species Real-Time PCR (test code 91476); Trichomonas vaginalis RNA, Qualitative, TMA, Males (test code 90801); Mycoplasma genitalium, rRNA, TMA (test code 91475).

Visit the Test Directory to order the right test for your patients today

Test codes may vary by location. Please contact your local laboratory for more information.

​References:

  1. Gaydos CA, Manhart LE, Taylor SN, et al. Molecular testing for Mycoplasma Genitalium in the United States: Results from the Ames Prospective Multicenter Clinical Study. J Clin Microbial. 2019;57(11). doi:10.1128/jcm.01125-19
  2. CDC. Sexually Transmitted Infections Treatment Guidelines, 2021. Mycoplasma genitalium. Published July 22, 2021. Accessed September 13, 2021. https://www.cdc.gov/std/treatment-guidelines/mycoplasmagenitalium.htm
  3. Napierala Mavedzenge S, Weiss HA. Association of Mycoplasma genitalium and HIV infection: a systematic review and meta-analysis. AIDS. 2009;23(5):611-620. doi:10.1097/QAD.0b013e328323da3e
  4. Ronda J, Gaydos CA, Perin J, et al Does the Sex Risk Quiz predict Mycoplasma genitalium infection in urban adolescents and young adult women? Sex Transm Dis. 2018;45(11):728-734.doi:10.1097/OLQ
  5. Mena, L., Wang, X., Mroczkowski, T. F., & Martin, D. H. (2002). Mycoplasma genitaliuminfections in asymptomatic men and men with urethritis attending a sexually transmitted diseases clinic in New Orleans. Clin Infect Dis, 35(10), 1167–1173. https://doi.org/10.1086/343829
  6. Workowski KA. Bolan GA. CDC. Sexually transmitted diseases treatment guidelines. 2015. published correction appears in MMWR Recomm Rep. 2015;64(33):9241. MMWR Recomm Rep. 2015;64(RR-03):1-137